Flonase Flonase Flonase can relieve multiple nasal symptoms of congestion, sneezing, and itchy, runny nose. Flonase Nasal Spray is for topical administration to the nasal mucosa by means of a metering, atomizing spray pump.Flonase Flonase Flonase can relieve multiple nasal symptoms of congestion, sneezing, and itchy, runny nose. Flonase Nasal Spray is for topical administration to the nasal mucosa by means of a metering, atomizing spray pump.